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. 2015 Oct 30;7(11):8987–9004. doi: 10.3390/nu7115445

Table 4.

Structures and activities of polyphenol inhibitors against β-catenin/Tcf.

Compound Structure β-Catenin IC50 (μM)
PKF118-744 graphic file with name nutrients-07-05445-i035.jpg 2.4 [73,74,75,76]
CGP049090 graphic file with name nutrients-07-05445-i036.jpg 8.7 [73,74,75,76]
PKF118-310 graphic file with name nutrients-07-05445-i037.jpg 0.8 [73,74,75,76]
ZTM00990 graphic file with name nutrients-07-05445-i038.jpg 0.64 [73,74,75,76]
BC21 graphic file with name nutrients-07-05445-i039.jpg Not Determined [73,77]
Ethacrynic acid graphic file with name nutrients-07-05445-i040.jpg ~70 [73,78,79]
Ethacrynic acid derivative graphic file with name nutrients-07-05445-i041.jpg ~5 [73,79]
PKF115-584 graphic file with name nutrients-07-05445-i042.jpg 3.2 [73,74,75,76]
PNU-74654 graphic file with name nutrients-07-05445-i043.jpg Not Determined [73,74,75,76]