. 2015 Nov 3;7(11):9046–9078. doi: 10.3390/nu7115447

Table 9.

Changes in the liver lipid peroxidation and antioxidant defense systems in NFD or HFD supplied mice.

Items Groups	Lipid Peroxidation	Antioxidant Defense System
Items Groups	Malondialdehyde (nM/mg Tissue)	Glutathione (μM/mg Tissue)	Catalase (U/mg Tissue)	SOD (U/mg Tissue)
Controls
Intact	10.9 ± 1.7	33.5 ± 6.7	30.6 ± 9.1	2.8 ± 0.6
HFD	28.4 ± 3.4 ^a	12.1 ± 1.9 ^a	10.4 ± 2.6 ^a	1.0 ± 0.1 ^a
Reference
Simvastatin	17.8 ± 2.2 ^a^c	19.8 ± 4.1 ^ac	18.8 ± 1.8 ^ac	2.0 ± 0.2 ^ac
Metformin	20.1 ± 2.0 ^a^c	18.1 ± 1.9 ^ac	17.5 ± 1.9 ^ac	1.9 ± 0.2 ^ac
GT 400 mg/kg	23.6 ± 2.7 ^a^c	16.5 ± 1.7 ^ac	15.5 ± 1.5 ^ac	1.4 ± 0.1 ^ac
fGT treated
400 mg/kg	15.2 ± 3.2 ^a^cd	26.4 ± 4.3 ^bcd	22.1 ± 3.6 ^bcd	2.3 ± 0.3 ^cd
200 mg/kg	17.7 ± 1.7 ^a^cd	21.4 ± 2.4 ^acd	19.1 ± 1.8 ^acd	2.0 ± 0.1 ^acd
100 mg/kg	20.1 ± 1.9 ^a^cd	18.8 ± 1.1 ^acd	17.7 ± 1.3 ^ace	1.9 ± 0.1 ^acd

Values are expressed as mean ± SD of eight mice. NFD, normal fat pellet diet; HFD, high fat diet; GT, green tea extracts; fGT, Aquilariae lignum-fermented green tea extracts; SOD, superoxide dismutase. Simvastatin and metformin were administrated at dose levels of 10 and 250 mg/kg, respectively. ^a p < 0.01 and ^b p < 0.05 as compared with intact control; ^c p < 0.01 as compared with HFD control; ^d p < 0.01 and ^e p < 0.05 as compared with GT 400 mg/kg.