Effect of ovariectomy and pomegranate peel extract consumption for 30 days on bone parameters in mice. (A) Bone mineral density analysis of left femur by X-ray radiation micro-CT. Mice were sham-operated, SH or ovariectomized, OVX and fed standard diet AIN-93 (Control) or standard diet enriched with 2g/kg of pomegranate peel extract, PGPE representing a dose of 10 mg polyphenols/kg body weight/day (ellagic acid equivalent) for 30 days. Each group contained 10 mice. Results are presented as means ± standard error of the mean, SEM. # p < 0.005 OVX Control versus SH Control group. * p < 0.05 OVX PGPE versus OVX Control. (B) Representative microCT images of the distal left femur for each group: SH Control, OVX Control and OVX PGPE. Scale bars, 1 mm.