Table 2.
Effect of ovariectomy and pomegranate peel extract consumption for 30 days on bone micro-architectural parameters in mice.
| Sham | Ovariectomized | ||
|---|---|---|---|
| Normal Diet | Normal Diet | PGPE Diet | |
| (SH) | (OVX) | (OVX+PGPE) | |
| BV/TV (%) | 12.7 ± 0.9 | 9.7 ± 0.6 # | 11.9 ± 0.76 * |
| TbTh (mm) | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 |
| TbN (mm−1) | 2.0 ± 0.1 | 1.5 ± 0.1 # | 1.8 ± 0.07 * |
| TbSP (mm) | 0.2 ± 0.0 | 0.3 ± 9.97E-03 # | 0.3 ± 0.0 |
| SMI | 2.5 ± 0.1 | 2.6 ± 0.1 | 2.4 ± 0.04 * |
| Conn Dn (mm−3) | 278.4 ± 26.5 | 223.5 ± 8.8 | 224.3 ± 12.7 |
| Tb Pf (mm−1) | 25.5 ± 1.1 | 27.7 ± 1.0 | 23.2 ± 1.2 |
| Po tot (%) | 87.3 ± 1.0 | 90.3 ± 0.61 # | 88.1 ± 0.76 * |
| BS/TV (mm−1) | 8.9 ± 0.5 | 6.7 ± 0.32 # | 7.9 ± 0.31 * |
Mice were sham-operated, SH or ovariectomized, OVX and fed standard diet AIN-93 (Control) or standard diet enriched with 2g/kg of pomegranate peel extract, PGPE representing a dose of 10 mg polyphenols/kg body weight/day (ellagic acid equivalent) for 30 days. Each group contained 10 mice. Values represent means ± standard error of the mean, SEM. # p < 0.005 OVX Control versus SH Control group. * p < 0.05 OVX PGPE versus OVX Control. Abbreviations: BV/TV: Per cent bone volume; TbTh: trabecular thickness; TbN: trabecular number; TbSP: trabecular spacing; SMI: structure model index; ConnDn: connectivity density; Tb Pf: trabecular pattern factor; Po tot: total porosity; BS/TV: bone surface density.