Table 3.

Metabolic parameters of participants at baseline and week 12 of intervention with C. forskohlii extract (n = 15 in each group).

Parameter	Baseline	Week 12	p Value
Fasting blood glucose (mmol/L)			Group	0.9
Experimental	5.3 ± 0.5	5.5 ± 1.0	Time	0.8
Placebo	5.3 ± 1.0	5.5 ± 1.4	Interaction	1
Triglycerides (mmol/L)			Group	0.2
Experimental	1.2 ± 0.5	1.1 ± 0.7	Time	0.5
Placebo	1.5 ± 1.0	1.4 ± 0.6	Interaction	0.8
Total cholesterol (mmol/L)			Group	0.9
Experimental	4.1 ± 1.2	3.7 ± 0.9	Time	0.08
Placebo	4.1 ± 1.1	4.5 ± 0.7	Interaction	0.9
HDL-C (mmol/L)			Group	0.4
Experimental	0.9 ± 0.4	1.2 ± 0.5 *	Time	0.01
Placebo	1.1 ± 0.6	1.3 ± 0.5 *	Interaction	0.7
LDL-C (mmol/L)			Group	0.6
Experimental	2.76 ± 1.0	2.83 ± 1.0	Time	0.5
Placebo	2.5 ± 1.7	2.8 ± 0.9	Interaction	0.7
HDL:LDL (mmol/L)			Group	0.6
Experimental	0.4 ± 0.2	0.5 ± 0.3	Time	0.7
Placebo	0.5 ± 0.1	0.6 ± 0.4	Interaction	0.9
Insulin (mU/L)			Group	0.8
Experimental	9.6 ± 5.7	6.1 ± 2.3	Time	0.2
Placebo	6.8 ± 3.8	8.5 ± 4.1	Interaction	0.001
HOMA-IR			Group	1
Experimental	2.3 ± 1.5	1.5 ± 0.7	Time	0.5
Placebo	1.4 ± 0.9	2.1 ± 1.4	Interaction	0.01
Ghrelin (pg/mL)			Group	0.6
Experimental	622 ± 127	647 ± 143	Time	0.4
Placebo	643 ± 209	686 ± 208	Interaction	0.9
Leptin (pg/mL)			Group	1
Experimental	33938 ± 4117	38783 ± 3451	Time	0.8
Placebo	36286 ± 5120	32701 ± 9609	Interaction	0.5

Values are expressed as mean ± SD. * p < 0.05, compared to baseline for each intervention. HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HOMA-IR, Homeostatic model assessment of insulin resistance