Skip to main content
. 2015 Nov 25;6:600. doi: 10.3389/fimmu.2015.00600

Figure 1.

Figure 1

MS and control-derived rIgG binding to neurofilament light (NF-L) by solid phase ELISA. MS-derived rIgG (n = 13) and control rIgG (n = 8) derived from a germinoma were tested by solid phase ELISA for binding to NF-L. The specific samples included in the assay are shown in the Supplementary Material. Each dot or square represents the binding of a single rIgG. The dashed line indicates the mean +2 SD of the control germinoma-derived cohort (0.76). Values above this line were determined to be positive (95% CI). To correct for non-specific binding, the reported ELISA signal (ΔOD) was calculated by subtracting the signal generated by binding to glyceraldehyde 3-phosphate dehydrogenase (GADPH) from that of the NF-L. The mean and SD are shown for each data set. Statistical differences are indicated when significant. Data associated with each rIgG for the MS and control groups are shown in the Supplementary Material.