Table 1.
Factors Associated with Low Limiting-Antigen Avidity Results Among Individuals from Guangxi, China Infected More Than 2 Years
| LAg-Avidity (<1.5 OD-n) | LAg-Avidity (<3.0 OD-n) | |||
|---|---|---|---|---|
| % Misclassified | OR (95% CI) | % Misclassified | OR (95% CI) | |
| All | 1.1% (4/362) | — | 5.5% (20/362) | — |
| Age (years) | ||||
| 23–30 | 1.5% (1/67) | 1 | 5.6% (4/67) | 1 |
| 31–35 | 0.0% (0/99) | — | 5.1% (5/99) | 0.84 (0.22–3.24) |
| 36–40 | 0.9% (1/106) | 0.63 (0.4–10.2) | 5.7% (6/106) | 0.95 (0.26–3.48) |
| 41–60 | 2.2% (2/90) | 1.50 (0.13–16.9) | 5.6% (5/90) | 0.92 (0.24–3.59) |
| Duration of infection (years) | ||||
| 2.0–3.8 | 0.0% (0/90) | 1 | 5.6% (5/90) | 1 |
| 3.9–5.4 | 4.4% (4/93) | — | 9.7% (9/93) | 1.82 (0.58–5.67) |
| 5.5–6.9 | 0.0% (0/86) | — | 3.5% (3/86) | 0.61 (0.14–2.65) |
| 7.0–13.5 | 0.0% (0/93) | — | 3.2% (3/93) | 0.57 (0.13–2.44) |
| Gender | ||||
| Male | 0.6% (2/319) | 1 | 4.7% (15/319) | 1 |
| Female | 4.3% (2/43) | 7.73 (1.06–56.4) | 11.6% (5/43) | 2.67 (0.92–7.75) |
| Race | ||||
| Han | 0.9% (3/324) | 1 | 4.3% (14/324) | 1 |
| Zhang | 4.4% (1/23) | 4.86 (0.49–48.7) | 30.8% (5/23) | 6.15 (1.99–19.0) |
| Unkown | 0.0% (0/15) | — | 6.7% (1/15%) | 1.58 (0.19–12.9) |
| Risk factor | ||||
| PWID | 0.6% (2/346) | 1 | 4.6% (16/346) | 1 |
| FSW | 15.4% (2/13) | 31.3 (4.0–242) | 30.8% (4/13) | 9.2 (2.55–33.0) |
| MSM | 0.0% (0/1) | — | 0.0% (0/1) | — |
| PRG | 0.0% (0/2) | — | 0.0% (0/2) | — |
| CD4 (cells/μl) | ||||
| >500 | 1.8% (2/112) | 1 | 4.5% (5/112) | 1 |
| 500-200 | 0.0% (0/1239) | — | 3.8% (7/184) | 0.85 (0.26–2.73) |
| <200 | 3.0% (2/66) | 1.72 (0.24–12.5) | 12.1% (8/66) | 2.95 (0.92–9.43) |
Odds ratios with p-values < 0.05 are in bold.
LAg, limiting–antigen; OD-n, normalized optical density; OR, odds ratio; PWID, people who inject drugs; FSW, female sex worker; MSM, men who have sex with men; PRG, pregnancy screen; CD4, CD4 T cell count.