FIG. 6.

(A) The expression of vWF was observed in the subcutaneous site. (B) The degree of vascularization was evaluated according to the number of vessels for anti-vWF immunostaining. In the implanted subcutaneous tissue, the number of vessels per square millimeter was counted. At 28 days after treatment, specimens were obtained from DM-sham mice (n=5), recipient SCID mice treated with islets alone (n=5), 4 MSC sheets alone (n=5), 2000 islets with MSCs (n=5), and 4 islets+MSC sheet (n=6). *p<0.05, **p<0.01. vWF, von Willebrand factor.