. 2015 Nov 30;13:373. doi: 10.1186/s12967-015-0732-5

Table 2.

mRNA expression of different genes involved in de novo lipogenesis in human visceral adipose tissue

	Non-obese subjects (N = 15)	MO-low-IR subjects (N = 15)	MO-high-IR subjects (N = 15)
SIRT3	0.029 ± 0.014	0.021 ± 0.015	0.009 ± 0.006^a*
PDHB	0.460 ± 0.170	0.244 ± 0.066^a	0.248 ± 0.081^a
ACC1	1.87 ± 0.43	1.15 ± 0.52^a	0.91 ± 0.59^a
ACSS2	1.14 ± 0.29	0.78 ± 0.42^a	0.80 ± 0.39^a
ACLY	1.01 ± 0.79	0.42 ± 0.08^a	0.31 ± 0.06^a
PPARγ	1.12 ± 0.65	2.72 ± 1.89^a	2.51 ± 0.87^a
SREBP-1c	0.271 ± 0.172	0.131 ± 0.072^a	0.116 ± 0.067^a
FASN	0.285 ± 0.088	0.148 ± 0.040^a	0.124 ± 0.020^a

MO-low-IR morbidly obese subjects with low insulin resistance, MO-high-IR morbidly obese subjects with high insulin resistance

^aP < 0.05 significant differences with respect to the non-obese group

* P < 0.05 significant differences between morbidly obese patients with low and high insulin resistance. All significant differences are adjusted for sex