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. 2015 Nov 30;17:344. doi: 10.1186/s13075-015-0800-5

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© Paulissen et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Proportions of chemokine receptor expressing memory Th cells differ between ACPA⁺ and ACPA⁻ RA patients. a Fraction of CD4⁺ T cell population within the total lymphocyte population of 27 ACPA⁺ and 27 ACPA⁻ patients with RA. b Fraction of memory CD4⁺ T cell population within the total CD4⁺ T cell population of 27 ACPA⁺ and 27 ACPA⁻ patients with RA. c Chemokine receptor and CD161 expression on peripheral blood memory (CD45RO⁺) CD4⁺CD25⁻ T cells from matched ACPA⁺ and ACPA⁻ patients with RA, measured by flow cytometry. For statistical analysis Wilcoxon matched-pairs signed-ranks test was performed (* = p < 0.05).