Figure 2. Dendrogram showing inter-strain relatedness of P. falciparum strains carrying the C580Y Pfkelch mutation obtained from patients with a first presentation of uncomplicated falciparum malaria in Buntharik district hospital in Ubon Ratchatani province in eastern Thailand.
Complete microsatellite typing was successful in 57/65 (88%) of parasite strains with the C580Y mutation. Microsatellite types were compared to 20 typed strains from Guinea16. Cluster analysis was based on typing of 9 microsatellites using genetic similarity indexes obtained by unweighted pair group method arithmetic averages (UPGMA). The analysis revealed 2 separate clusters within the Ubon Ratchathani isolates.