Table 4. Adverse events in HIV-infected patients with acute or chronic HCV infection.

Parameter*	Acute HCV infection	Chronic HCV infection
	All (N = 24)	Arm A (N = 12)	Arm B (N = 10)	Arm C (N = 16)	Arm D (N = 11)	Arm E (N = 4)	Arm F (N = 28)	Arm G (N = 11)
Flu-like symptoms	7 (29)	4 (33)	3 (30)	4 (25)	4 (36)	2 (50)	9 (32)	3 (27)
Fatigue	6 (25)	4 (33)	4 (40)	6 (38)	2 (22)	1 (25)	8 (29)	2 (22)
Headache	2 (8)	1 (8)	1 (10)	1 (6)	1 (9)	0 (0)	3 (11)	1 (9)
Insomnia	6 (25)	4 (33)	3 (30)	4 (25)	3 (27)	1 (25)	9 (32)	2 (18)
Irritability	1 (4)	1 (8)	1 (10)	2 (13)	1 (9)	0 (0)	3 (11)	1 (9)
Depression	1 (4)	0 (0)	1 (10)	1 (6)	0 (0)	0 (0)	2 (7)	0 (0)
Anorexia	4 (17)	2 (17)	1 (10)	2 (13)	2 (22)	1 (25)	5 (18)	2 (18)
Diarrhea	1 (4)	0 (0)	0 (0)	1 (6)	1 (9)	0 (0)	2 (7)	0 (0)
Cough	1 (4)	0 (0)	0 (0)	1 (6)	1 (9)	0 (0)	2 (7)	0 (0)
Oral ulcer	2 (8)	1 (8)	1 (10)	1 (6)	1 (9)	1 (25)	3 (11)	1 (9)
Dermatitis	3 (13)	3 (25)	3 (30)	3 (19)	2 (22)	1 (25)	7 (25)	3 (27)
Injection site reaction	1 (4)	0 (0)	0 (0)	1 (6)	0 (0)	0 (0)	1 (4)	1 (9)
Hair loss/alopecia	2 (8)	1 (8)	1 (10)	3 (19)	2 (22)	0 (0)	3 (11)	2 (22)
Anemia†	3 (13)	2 (17)	3 (30)	4 (25)	4 (36)	0 (0)	5 (18)	3 (27)
Leukopenia‡	2 (8)	1 (8)	2 (20)	3 (19)	3 (27)	0 (0)	3 (11)	2 (22)
Thrombocytopenia§	0 (0)	0 (0)	0 (0)	1 (6)	0 (0)	0 (0)	2 (7)	0 (0)

^*Values are numbers (percentages).

^†Anemia was defined as a nadir hemoglobin level <10 g/dL.

^‡Leukopenia was defined as a nadir absolute neutrophil count (ANC) <750 × 10⁶ cells/L

^§Thrombocytopenia was defined as a nadir platelet count <50 × 10⁹ cells/L.