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(A) HEMO/DYSP PV from a 12-year-old patient demonstrating (via histochemical staining) strong expression of NMM, P4H, LOX, and fibrillin in the spongiosa (arrow). Note also the expansion of HA staining across the thickness of the leaflet. Scale bar indicates 500 μm and applies to all panels of the figure. (B). Images demonstrating the region within the purple box in Part (A) of this figure at higher magnification. Scale bar indicates 500 μm and applies to all panels of the figure.
