TABLE V.
GENE ONTOLOGY ENRICHMENT OF THE MODULES FOR THE THREE CANCERS
| Module | Enriched GO terms | % | pvalue |
|---|---|---|---|
| Module 1 | GO:0006334 nucleosome assembly | 100 | 8.83E-21 |
| GO:0031497 chromatin assembly | 100 | 1.23E-20 | |
| GO:0065004 protein-DNA complex assembly | 100 | 1.88E-20 | |
| GO:0034728 nucleosome organization | 100 | 2.31E-20 | |
| GO:0006323 DNA packaging | 100 | 1.98E-19 | |
| GO:0006333 chromatin assembly or disassembly | 100 | 4.25E-19 | |
| GO:0034622 cellular macromolecular complex assembly | 100 | 1.96E-15 | |
| GO:0034621 cellular macromolecular complex subunit organization | 100 | 5.62E-15 | |
| GO:0006325 chromatin organization | 100 | 9.46E-15 | |
| GO:0051276 chromosome organization | 100 | 9.11E-14 | |
| GO:0065003 macromolecular complex assembly | 100 | 1.59E-12 | |
| GO:0043933 macromolecular complex subunit organization | 100 | 2.88E-12 | |
|
| |||
| Module 3 | GO:0000278 mitotic cell cycle | 57.14 | 1.31E-22 |
| GO:0022403 cell cycle phase | 57.14 | 1.12E-21 | |
| GO:0007049 cell cycle | 65.71 | 4.43E-21 | |
| GO:0022402 cell cycle process | 60.00 | 1.01E-20 | |
| GO:0000279 M phase | 51.43 | 4.62E-20 | |
| GO:0000280 nuclear division | 45.71 | 2.14E-19 | |
| GO:0007067 mitosis | 45.71 | 2.14E-19 | |
| GO:0000087 M phase of mitotic cell cycle | 45.71 | 2.82E-19 | |
| GO:0048285 organelle fission | 45.71 | 3.94E-19 | |
| GO:0051301 cell division | 40.00 | 2.81E-14 | |
| GO:0051726 regulation of cell cycle | 40.00 | 1.24E-13 | |
| GO:0007346 regulation of mitotic cell cycle | 28.57 | 3.67E-11 | |
|
| |||
| Module 8 | GO:0006955 immune response | 46.20 | 3.70E-62 |
| GO:0006952 defense response | 37.43 | 5.36E-46 | |
| GO:0006954 inflammatory response | 23.98 | 1.89E-31 | |
| GO:0009611 response to wounding | 26.90 | 1.94E-28 | |
| GO:0009615 response to virus | 10.53 | 2.00E-15 | |
| GO:0006959 humoral immune response | 9.36 | 4.56E-15 | |
| GO:0006935 chemotaxis | 11.70 | 7.23E-15 | |
| GO:0042330 taxis | 11.70 | 7.23E-15 | |
| GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 7.02 | 2.49E-14 | |
| GO:0002252 immune effector process | 10.53 | 6.84E-14 | |
| GO:0019882 antigen processing and presentation | 8.77 | 2.16E-13 | |
| GO:0002684 positive regulation of immune system process | 12.28 | 1.04E-12 | |
| GO:0045087 innate immune response | 9.94 | 1.60E-12 | |
| GO:0007626 locomotory behavior | 12.87 | 1.61E-12 | |
| GO:0050778 positive regulation of immune response | 9.94 | 3.48E-12 | |
| GO:0002449 lymphocyte mediated immunity | 7.60 | 9.84E-12 | |
| GO:0019724 B cell mediated immunity | 7.02 | 1.55E-11 | |
| GO:0002250 adaptive immune response | 7.60 | 3.19E-11 | |
| GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 7.60 | 3.19E-11 | |
| GO:0002526 acute inflammatory response | 8.19 | 3.85E-11 | |
|
| |||
| Module 13 | GO:0006955 immune response | 40 | 1.19E-14 |