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. Author manuscript; available in PMC: 2015 Nov 30.
Published in final edited form as: Ann Hum Genet. 2005 Jul;69(0 4):429–442. doi: 10.1046/j.1529-8817.2005.00164.x

Table 6.

Empirical power using sample sizes obtained through asymptotic approximation for high penetrances*

ε = 0 ε = 0.005 ε = 0.01
Dominant
  p = 0.05 0.840 0.842 0.866
  p = 0.20 0.840 0.846 0.840
  p = 0.70 0.896 0.896
Recessive
  p = 0.05 0.780
  p = 0.20 0.808 0.702
  p = 0.70 0.796 0.836 0.804
Multiplic.
  p = 0.05 0.872
  p = 0.20 0.796 0.830 0.852
  p = 0.70 0.790 0.818 0.814
Additive
  p = 0.05 0.774 0.796
  p = 0.20 0.800 0.764 0.890
  p = 0.70 0.780 0.730 0.816
*

The critical value is 5.3267 (which corresponds to the significance level of 5 × 10−8 under normality); Dominant model: f2 = f1 = 0.4, f0 = 0.1; Recessive model: f2 = 0.4, f1 = f0 = 0.1; Multiplicative model: f2 = 0.4, f1 = 0.2, f0 = 0.1; Additive model: f2 = 0.4, f1 = 0.25, f0 = 0.1.