Table 3.

mRNA fold changes of mitochondrial, ETC and synaptic genes in mutant Htt neurons treated with Mdivi1

Gene	mRNA fold changes
	25 µM Mdivi	50 µM Mdivi
	Mean	Mean
Mitochondrial dynamics genes
DRP1	−1.6*	−1.4*
FIS1	−1.6*	−1.1
Mfn1	3.2**	1.8**
Mfn2	2.2**	1.9**
Cyclophilin D	−1.6*	−1.4*
OPA1	1.7*	2.6**
VDAC	−1.4*	−1.1
Mitochondria-encoded electron transport chain genes
ND1—Complex I	−1.1	1.7*
ND3—Complex I	−1.2	1.7*
ND6—Complex I	−1.2	1.5*
Cyt B—Complex III	−1.2	1.3
COX1—Complex IV	−1.2	1.6*
COX2—Complex IV	−1.2	1.6*
COX3—Complex IV	−1.3	1.4*
ATP6—Complex V	−1.4*	1.3
Synaptic genes
Synaptophysin	1.5*	2.1**
PSD-95	1.2	1.3
Synapsin 1	1.4*	1.6*
Synapsin 2	3.3**	1.8**
Synaptobrevin 1	2.6**	2.2**
Synaptobrevin 2	1.2	1.2
Neurogranin	1.2	2.2**
GAP43	1.7*	3.2**
Synaptopodin	1.2	2.1*