Table 2.
List of significant genotype-methylation associations identified
| SNP | CpG probe | Chr. | Probe location (hg19) | SNP location (hg19) | Adj. P-value All samples | Adj. P-value OA |
|---|---|---|---|---|---|---|
| rs6976 | cg18099408 cg15147215 cg18591801 |
3p21.1 | 52552593 52552868 52553433 |
52728804 | 3.19 × 10−8 0.005 0.004 |
3.73 × 10−6 0.04 0.04 |
| rs10948172 | cg13979708 cg19254793 cg20913747 cg18551225 |
6p21.1 | 44695318 44695348 44695427 44695536 |
44777691 | 9.83 × 10−6 0.008 8.75 × 10−13 1.70 × 10−10 |
6.2 × 10−5 0.009 4.9 × 10−12 1.12 × 10−10 |
| rs3204689 | cg12031962 | 15q21.3 | 58353849 | 58246802 | 1.03 × 10−10 | 2.0 × 10−8 |
| rs143383 | cg14752227 | 20q11 | 34000481 | 34025983 | 0.001 | 0.01 |
Shown are the P-values from all of the samples combined and OA samples only. Adj. P-value represents the Benjamini–Hochberg corrected P-value.