Fig. 4.
Regional association plot of the chromosome 3 association peak. Association results for Mb 45.5–47 (Hg19) of chromosome 3 in a subset of individuals genotyped for CCR5Δ32 (n = 5,559). P values were calculated by linear regression, including covariates. The blue diamond, red square, and red diamond indicate the association strength of the top SNP (rs4317138, P = 7.7 × 10−22), Hap-P1 (P = 1.8 × 10−19), and CCR5Δ32 (P = 1.6 × 10−16), respectively. The dashed line indicates genome-wide significance (P = 5 × 10−8).