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Acute effect of anti-VEGF treatment on rotarod performance. In mice bearing size-matched tumors (1 cm in diameter), rotarod test was carried out at different time points after B20 treatment. The average time to fall from the rotating cylinder was normalized to the value from each mouse on the first day and presented as relative rotarod endurance. Representative of at least three independent experiments (n = 8), data presented are mean ± SEM. *P < 0.05.
