Table 4. Effect of diuretic use and hemodialysis vintage on association between acid suppressive therapy and serum magnesium.
Proton pump inhibitor | H2 receptor antagonist | No acid-suppressive medications | |||
---|---|---|---|---|---|
β-coefficient±s.e. | P value | β-coefficient±s.e. | P value | reference | |
Furosemide (n = 291) | -0.054±0.047 | 0.249 | 0.006±0.085 | 0.565 | - |
Shorter dialysis vintage <24 mo (n = 188) | 0.069±0.082 | 0.421 | 0.017±0.126 | 0.984 | - |
Furosemide+shorter dialysis vintage <24 mo(n = 96) | 0.0139±0.092 | 0.778 | 0.142±0.19 | 0.41 | - |
Abbreviation: H2, histamine-2. Reference category is patients on no acid-suppressive medications. β-coefficients ± s.e’s and P values are provided for each variable. Adjusted models includes age, dialysis vintage, sex, Diabetes mellitus, Kt/V, systolic blood pressure, albumin, potassium, C-reactive protein, sodium, blood urea nitrogen, parathyroid hormone, phosphorus, calcium, hemoglobin, furosemide, antiplatelet drug, vitamin K antagonist, angiotensin converting enzyme inhibitor or angiotensin II receptor blocker, phosphate binder, vitamin D receptor antagonist, atrial fibrillation, gastric hemorrhage, cerebral infarction, and ischemic heart disease.