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. 2015 Nov 30;10(11):e0142756. doi: 10.1371/journal.pone.0142756

Fig 1. Overall regional brain atrophy pattern of AD subtypes in voxel-based morphometry.

Fig 1

Voxel-wise whole-brain comparison of regional GM volume after correction for multiple comparisons using family-wise error correction at p < 0.05 (k = 100). (A) to (D) show the regional patterns of GM volume loss in each AD subtype compared with CN. (A) CN vs. BI, (B) CN vs. HA, (C) CN vs. CA and (D) CN vs. BS. GM, Gray matter; AD, Alzheimer’s disease; CN, Cognitively normal; BI, Both impaired; HA, Hippocampal atrophy only; CA, Cortical atrophy only; BS, Both spared.