. 2015 Nov 26;7:615–627. doi: 10.2147/CEOR.S92078

Table 1.

Utility algorithms identified from the systematic literature review and mapping database

Author, year	Questions or scores included in algorithm	Mapping Equation		Characteristics of surveyed population used to generate mapping algorithm	Algorithm performance statistics		Range of possible values from algorithm
Author, year	Questions or scores included in algorithm	Mapping Equation			Observed in original survey data	Predicted using original survey data	Range of possible values from algorithm
Dobrez, 2007 (and reported in Hess, 2013)⁹,¹⁹	PWB1:“I have a lack of energy” PWB2: “I have nausea” FWB1 : “I am able to work (include work at home)” FWB2: “I am able to enjoy life”	Utility (TTO) = 1		Female: 47.0% Age (years): 57.0 ECOG performance status (0/1/2/3/unknown): 29.1%/26.4%/32.5%/1 1%l1% Prevalent cancer types: 17.5% breast cancer, 13.2% prostate and 11.4% head and neck Total FACT-G scores: n.r.	Mean: 0.805 SD: 0.284 Median: n.r. Range:0 to 1	Mean: 0.832 SD: 0.121 Median: n.r Range: 0.456 to 1.0 R2:nr MAE: 0.19	0.456–1.00
Dobrez, 2007 (and reported in Hess, 2013)⁹,¹⁹		$\begin{array}{l} + P W B 1 {\begin{matrix} - 0.2222, \\ - 0.1137, \\ 0, \end{matrix} \\ + P W B 2 {\begin{matrix} - 0.1537, \\ 0, \end{matrix} \\ + F W B 1 {\begin{matrix} - 0.04311, \\ 0, \end{matrix} \\ + F W B 2 {\begin{matrix} - 0.1254, \\ - 0.0641, \\ - 0.0345, \\ 0, \end{matrix} \end{array}$	if “very much” or “quite a bit” if “somewhat” or “a little bit” if “none at all” if “very much” or “quite a bit” otherwise if “not at all” or “a little bit” otherwise if “not at all” or “a little bit” if “somewhat” if “quite a bit” if “very much”		Mean: 0.805 SD: 0.284 Median: n.r. Range:0 to 1		0.456–1.00
Cheung, 2009¹⁸	PWB total score EWB total score FWB total score	Utility (EQ–5D)		Female: 62.9% Age (years): 49.3 ECOG performance status (0/1/2/3/unknown): 32.8%/40.3%/23.5%/3.4%/n.r. Prevalent cancer types: 37.1% breast cancer, 18.6% head and neck, 10.9% colorectal Mean total FACT-G scores: 81.1	Mean: 0.803 SD:0.156 Median: 0.769 Range: 0.246 to 1.00	Mean: 0.811 SD:0.130 Median: 0.822 Range: 0.393 to 0.999 R2:0.417 MAE: 0.095	0.238–0.998
Cheung, 2009¹⁸	PWB total score EWB total score FWB total score	= 0.238 + 0.014 × PWB total + 0.006 × EWB total + 0.008 × FWB total			Mean: 0.803 SD:0.156 Median: 0.769 Range: 0.246 to 1.00		0.238–0.998
Longworth, 2014 (OLS)⁷,²⁰	PWB1: “I have lack of energy” PWB2: “I have trouble meeting the need of family” PWB3: “I have pain” EWB1: “I feel sad” EWB2: “I am losing hope” FWB1: “I am able to work”	Utility (EQ–5D)=0.186		Female: 51.0% Age (years): 59.3 ECOG performance status (0/1/2/3/unknown): 23.4%/48.4%/23.5%/4.7%/n.r. Prevalent cancer types: 11 types of advanced cancer including ovarian cancer. Mean total FACT-G scores: 78	Mean: 0.721 SD: 0.223 Median: 0.735 Range: −0.135 to 1.00	Mean: 0.721 SD: 0.163 Median: 0.755 Range: 0.115 to 0.962 R2: 0.535 MAE: 0.111	0.016–0.956
		$+ P W B 1 {\begin{matrix} 0, \\ 0.045, \\ 0.036, \\ 0.071, \\ 0.118, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
		$+ P W B 2 {\begin{matrix} 0, \\ 0.028, \\ 0.049, \\ 0.088, \\ 0.098, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if” A little bit” if “not at all”
		$+ P W B 3 {\begin{matrix} 0, \\ 0.125, \\ 0.219, \\ 0.240, \\ 0.342, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
		$+ E W B 1 {\begin{matrix} 0, \\ 0.085, \\ 0.019, \\ 0.006, \\ 0.004, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
		$+ E W B 2 {\begin{matrix} 0, \\ - 0.081, \\ - 0.007, \\ 0.013, \\ 0.060, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
		$+ F W B 1 {\begin{matrix} 0.152, \\ 0.150, \\ 0.130, \\ 0.113, \\ 0, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
Longworth, 2014 (Tobit)¹⁷,²⁰	PWB1: “I have lack of energy” PWB2: “I have pain” FWB1: “I am able to work” FWB2: “I am able to enjoy life”	Utlity (EQ–5D) = 0.23 1				Mean: 0.723 SD: 0.161 Median: 0.738 Range: 0.135 to 0.957 R2: n.r. MAE: 0.181	0.133–1.00
		$+ P W B 1 {\begin{matrix} 0, \\ 0.055, \\ 0.053, \\ 0.113, \\ 0.200, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
		$+ P W B 2 {\begin{matrix} 0, \\ 0.164, \\ 0.255, \\ 0.293, \\ 0.431, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
		$+ F W B 1 {\begin{matrix} 0.151, \\ 0.149, \\ 0.110, \\ 0.097, \\ 0, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”
		$+ F W B 2 {\begin{matrix} - 0.057, \\ - 0.010, \\ - 0.012, \\ - 0.098, \\ 0, \end{matrix}$	if “very much” if “quite a bit” if “Somewhat” if “A little bit” if “not at all”

Abbreviations: n.r., not reported; ECOG, Eastern Cooperative Oncology Group; SD, Standard Deviation; MAE, Mean Absolute Error; PWB, Physical well-being; FWB, Functional well-being; EWB, Emotional well-being.