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. Author manuscript; available in PMC: 2015 Nov 30.
Published in final edited form as: Curr Mol Pharmacol. 2015;8(1):12–21. doi: 10.2174/1874467208666150507103417

Fig. 4. Regulation of CaV1.2 channel activity by optimal expression of cDNA encoding CaV1.2 channel subunits and AKAP15.

Fig. 4

(A) Representative Ba2+ currents (Top) and current-voltage relationships (Bottom) of CaV1.2 channels expressed in tsA-201 cells by co-transfection of the indicated cDNAs encoding CaV1.2Δ1800, distal C-terminus (DCT), AKAP15, and 5 μM Forskolin (FSK). (B) Representative Ba2+ currents (Top) and current-voltage relationships (Bottom) of CaV1.2 channels expressed in tsA-201 cells by co-transfection of the indicated cDNAs encoding CaV1.2Δ1800, distal C-terminus (DCT), AKAP15, and 5 μM Forskolin (FSK) with wild-type CaV1.2Δ1800 and mutants S1700A, T1704A, and S1700A/T1704A. Mean±SEM; significance determined by ANOVA.