Table 3. Percentage of the Surface Area of the Large Airways with Normal Histology, Atypia, Low-grade Dysplasia & High-grade Dysplasia After NTCU Treatment.

Treatment group	N	Normal	Atypia	Low-grade Dysplasia	High-grade Dysplasia
15 weeks of NTCU (15 μmol)
S	11	100 ± 0
SN	14		26 ± 17.9	63.5 ± 17.5	8.72 ± 9.5
SN+C	14		38.5 ± 27.1	53.3 ± 23.3	6.6 ± 7.7
D	15	100 ± 0
DN	10	3.8 ± 6.7	25.3 ± 10.5	48.3 ± 9.2	22.7 ± 8.8†‡
DN+C	12	0.8 ± 1.8	23.2 ± 21.3	63.1 ± 20.4	12.3 ± 13.9
25 weeks of NTCU (25 μmol)
S	14	99.7 ± 1.1		0.3 ± 1.1
SN	13	4.9 ± 8.0	38.2 ± 16.2	48.5 ± 14.1	8.4 ± 7.7
SN+C	8	6.4 ± 15	41.4 ± 28.7	40.4 ± 29.1	11.8 ± 15.6
D	10	97.9 ± 5.3		2.1 ± 15.3
DN	7	3.5 ± 6.6	12.5 ± 35.6	48.5 ± 27.4	35.5 ± 21†‡
DN+C	10		5.42 ± 9.2	72.9 ± 14.9	21.3 ± 10.3

Percent of lesions are represented as the mean of total airways scored per group +/− SEM; 3 sections (each ~ 100 microns apart) were scored per mouse

^†significant p<0.05 compared to S

^‡significant p<0.05 compared to SN