Table 3.
Change in Scores From Baseline to Week 8a
| Scale | 10 mg |
20 mg |
40 mg |
|||
| Baseline | Week 8 | Baseline | Week 8 | Baseline | Week 8 | |
| MADRS | 32.631 (5.240) | 8.588 (7.770) | 28.368 (6.229) | 10.058 (9.984) | 31.0526 (7.152) | 8 (7.968) |
| DESS | 7.697 (1.327) | 4.100 (1.126) | 8.582 (2.143) | 4.582 (0.932) | 8.435 (1.267) | 4.315 (0.992) |
| ASEX | 6.360 (2.615) | 3.720 (1.341) | 7.413 (2.455) | 3.363 (1.267) | 7.358 (2.810) | 3.617 (1.543) |
| SDS | 9.387 (4.014) | 5.667 (2.673) | 7.210 (4.524) | 3.593 (2.981) | 8.197 (3.889) | 4.833 (2.556) |
| HDRS | 1.013 (1.023) | 0.278 (0.577) | 0.856 (1.003) | 0.232 (0.534) | 0.984 (1.009) | 0.214 (0.494) |
| CGI-S | 4.352 (2.235) | 2.176 (1.074) | 3.944 (1.865) | 2.000 (0.816) | 4.117 (1.764) | 2.059 (0.827) |
| CGI-I | 3.529 (2.042) | 1.882 (0.928) | 3.566 (1.092) | 1.789 (1.032) | 3.058 (1.283) | 1.529 (0.659) |
a
Data are presented as mean (SD).
Abbreviations: ASEX = Arizona Sexual Experience Scale, CGI-I = Clinical Global Impressions–Improvement, CGI-S = Clinical Global Impressions–Severity, DESS = Discontinuation Emergent Signs and Symptoms, HDRS = Hamilton Depression Rating Scale, MADRS = Montgomery-Asberg Depression Rating Scale, SDS = Sheehan Disability Scale.