Table 1.
Demographic and neuropsychological data (a = Mann-Whitney-Test, b = t-test, c = Fisher’s exact test, degree of freedom was 22 for all group comparisons, results presented as mean ± SD).
| PD patients with lower impulsivity (n = 16) | PD patients with higher impulsivity (n = 8) | p-value | ||
|---|---|---|---|---|
| Sex (female/male) | 6/10 | 2/6 | 0.667c | |
| Age (year) | 65 ± 6.59 | 68.88 ± 3.75 | 0.14b | |
| Duration since diagnosis | 7.41 ± 4.23 | 11.38 ± 5.21 | 0.054b | |
| Hoehn und Yahr OFF | 3 ± 0.89 | 2.62 ± 0.51 | 0.349a | |
| Hoehn und Yahr ON | 2.5 ± 1.03 | 2.25 ± 0.46 | 0.588a | |
| UPDRS III OFF | 35.06 ± 14.17 | 29.50 ± 5.15 | 0.177b | |
| UPDRS III ON | 24.19 ± 13.09 | 21.38 ± 6.34 | 0.759a | |
| LEDD—total (mg) | 600.94 ± 356.45 | 956.12 ± 475.51 | 0.051b | |
| LEDD—dopamine agonists (mg) | 180.62 ± 133.85 | 318.62 ± 181.68 | 0.046b | |
| MMSE | 28.69 ± 1.138 | 28.75 ± 1.275 | 0.928a | |
| BIS—total | 53.18 ± 7.60 | 70.37 ± 4.17 | 0.000b | |
| BIS—attention | 14.37 ± 2.80 | 18.375 ± 2.38 | 0.002b | |
| BIS—motor impulsivity | 19.00 ± 3.01 | 22.625 ± 2.32 | 0.007b | |
| BIS—non-planning | 19.81 ± 5.39 | 29.5 ± 3.92 | 0.000b |
Abbreviations: BIS, barratt impulsiveness scale; LEDD, levodopa equivalent daily dose; MMSE, mini–mental state examination; PD, Parkinson’s disease; SD, standard deviation; UPDRS, unified Parkinson’s disease rating scale.