Fig. 4.

Gene set enrichment analysis: A gene-set enrichment analysis (GSEA) was performed on differentially expressed genes between shRNA-MARK2 and controls. Two-fold change genes identified on NCI-H1993 (green), NCI-H1693 (blue) and NCI-H1650 (red) were chosen as inputs for A) Transcription factor targets or B) canonical pathways gene sets analysis. Negatively and positively enriched gene sets are shown in bars to the left and right of the zero line. A q-value ≤ 0.05 was used a significance threshold. Names of significantly enriched gene sets are shown on the y-axis.