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Median normalization of miRNA microarray data enabled identification of significantly differentially expressed miRNAs. Median signal intensities of miRNAs in serum after (AC) versus before chemotherapy (BC, n = 9), before (A) and after median normalization (B). White dots represent significantly differentially expressed microRNAs after normalization. Data points on the x-axis represent 163 miRNAs that are exclusively detected in BC serum.
