Table 2.

Bowel, urinary, and sexual domain scores at 24 months for UCLA-PCI and EPIC QoL instruments

	74 Gy in 37 fractions (n=676)		60 Gy in 20 fractions (n=686)		57 Gy in 19 fractions (n=692)		74 Gy vs 60 Gy p value*	74 Gy vs 57 Gy p value*	60 Gy vs 57 Gy p value*
	Number of patients with data	Median (IQR)	Number of patients with data	Median (IQR)	Number of patients with data	Median (IQR)
Bowel function (UCLA)	312 (46%)	93·8 (82·5–100·0)	310 (45%)	91·8 (79·3–100·0)	331 (48%)	93·8 (81·3–100·0)	0·064	0·77	0·12
Urinary function (UCLA)	311 (46%)	100·0 (81·8–100·0)	313 (46%)	100·0 (81·8–100·0)	334 (48%)	100·0 (83·5–100·0)	0·69	0·47	0·74
Sexual function (UCLA)	307 (45%)	27·1 (4·1–53·1)	300 (44%)	23·4 (7·3–57·3)	321 (46%)	26·0 (7·3–56·3)	0·39	0·33	0·92
Bowel function (EPIC)	95 (14%)	96·4 (89·3–96·4)	94 (14%)	96·4 (89·3–100·0)	100 (14%)	92·9 (85·7–98·2)	0·15	0·51	0·059
Bowel bother (EPIC)	95 (14%)	95·8 (87·5–100·0)	96 (14%)	95·8 (83·3–100·0)	101 (15%)	95·8 (79·2–100·0)	0·54	0·15	0·38
Bowel summary (EPIC)	93 (14%)	94·2 (88·5–98·1)	94 (14%)	94·2 (87·5–100·0)	99 (14%)	94·2 (84·6–98·1)	0·41	0·41	0·15
Urinary function (EPIC)	97 (14%)	100·0 (93·4–100·0)	99 (14%)	100·0 (88·4–100·0)	104 (15%)	100·0 (90·9–100·0)	0·18	0·84	0·11
Urinary bother (EPIC)	89 (13%)	89·3 (79·2–96·4)	95 (14%)	89·3 (78·6–96·4)	102 (15%)	90·5 (75·0–96·4)	0·64	0·72	0·38
Urinary summary (EPIC)	89 (13%)	91·0 (85·4–97·9)	95 (14%)	93·1 (82·7–97·9)	101 (15%)	93·8 (82·7–97·9)	1·00	0·91	0·93
Sexual function (EPIC)	89 (13%)	21·6 (0·0–60·0)	88 (13%)	21·6 (0·0–53·4)	98 (14%)	26·6 (0·0–58·4)	0·78	0·74	0·53
Sexual summary (EPIC)	92 (14%)	28·4 (15·2–62·5)	93 (14%)	23·7 (16·7–58·3)	99 (14%)	27·8 (13·8–61·2)	0·60	0·84	0·74

EPIC-50 was used for bowel and urinary domains and EPIC-26 for sexual domains. UCLA-PCI=University of California, Los Angeles Prostate Cancer Index. EPIC=Expanded Prostate Cancer Index Composite.

^*Mann-Whitney U test.