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. 2015 Dec 1;5:17604. doi: 10.1038/srep17604

Figure 3. Elovl6 deficiency suppresses lithogenic diet (LD)-induced hepatic lipid accumulation in Ldlr−/− mice.

Figure 3

(A) Representative photographs of livers from Elovl6+/+Ldlr−/− and Elovl6−/−Ldlr−/− mice fed an LD for 4 weeks. (B) The prevalence rate of gallstones in Elovl6+/+Ldlr−/− and Elovl6−/−Ldlr−/− mice fed an LD for 4 weeks (n = 8–10 per group). (C) Polarizing light microscopy of gallbladder bile from Elovl6+/+Ldlr−/− and Elovl6−/−Ldlr−/− mice fed an LD for 4 weeks (magnification, ×200). (D–F) Hepatic total cholesterol (TC) (D), triglyceride (TG) (E) and total bile acid (TBA) (F) levels in Elovl6+/+Ldlr−/− and Elovl6−/−Ldlr−/− mice fed a standard diet (SD) or an LD for 4 weeks (n = 8–13 per group). *P < 0.05, **P < 0.01.