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. 2015 Dec 1;5:17604. doi: 10.1038/srep17604

Figure 8. Effects of Elovl6 deficiency on hepatic mRNA and levels of proteins involved in inflammation, oxidative stress and fibrosis.

Figure 8

(A–C) Quantitative real-time PCR (qPCR) analysis of genes for inflammation (A), reactive oxygen species (ROS) generation (B) and fibrogenesis (C). (D) Immunoblot analysis of phosphorylated and total anti-phospho-c-Jun N-terminal kinase (JNK), α-smooth muscle actin (α-SMA) and GAPDH in the livers of Elovl6+/+Ldlr−/− and Elovl6−/−Ldlr−/− mice fed a standard diet (SD) or a lithogenic diet (LD) for 4 weeks. (E) Ratio between phosphorylated and total JNK and α-SMA and GAPDH on densitometry analysis (n = 2–4 per group). *P < 0.05, **P < 0.01.