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. 2015 Nov 11;7(11):5831–5843. doi: 10.3390/v7112909

Figure 3.

Figure 3

TLR-induced cytokine responses in blood cells from TOSV-infected patients and healthy controls. Blood cells were left unstimulated or stimulated with poly(A:U) (TLR3 ligand; 20 µg/mL) or Resiquimod-R848 (TLR7/8 ligand; 10 µg/mL). After 24 h, supernatants were collected and analyzed for cytokine levels. White squares indicate healthy controls and black triangles indicate TOSV-infected patients. N = 8 TOSV-infected patients and n = 7 healthy controls were evaluated. Data were analyzed using the non-parametric Mann–Whitney U test. * indicates p ≤ 0.05.