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. 2015 Mar;8(Spec Feature):49–53.

Table 3.

The REVEL Trial: Ramucirumab plus Docetaxel versus Placebo plus Docetaxel in Non–Small-Cell Lung Cancer

Efficacy measure Ramucirumab + docetaxel
(N = 628)
Placebo + docetaxel
(N = 625)
Overall survival
   Deaths, N (%) 428 (68) 456 (73)
   Median, mo 10.5 (95% CI, 9.5–11.2) 9.1 (95% CI, 8.4–10.0)
   Hazard ratio 0.86 (95% CI, 0.75–0.98)
   Stratified log-rank P value .024
Progression-free survival
   Events, N (%) 558 (89) 583 (93)
   Median, mo 4.5 (95% CI, 4.2–5.4) 3.0 (95% CI, 2.8–3.9)
   Hazard ratio 0.76 (95% CI, 0.68–0.86)
   Stratified log-rank P value <.001

CI indicates confidence interval.

Source: Cyramza (ramucirumab) injection prescribing information; December 2014.