Table 3.
Efficacy measure | Ramucirumab + docetaxel (N = 628) |
Placebo + docetaxel (N = 625) |
---|---|---|
Overall survival | ||
Deaths, N (%) | 428 (68) | 456 (73) |
Median, mo | 10.5 (95% CI, 9.5–11.2) | 9.1 (95% CI, 8.4–10.0) |
Hazard ratio | 0.86 (95% CI, 0.75–0.98) | |
Stratified log-rank P value | .024 | |
Progression-free survival | ||
Events, N (%) | 558 (89) | 583 (93) |
Median, mo | 4.5 (95% CI, 4.2–5.4) | 3.0 (95% CI, 2.8–3.9) |
Hazard ratio | 0.76 (95% CI, 0.68–0.86) | |
Stratified log-rank P value | <.001 |
CI indicates confidence interval.
Source: Cyramza (ramucirumab) injection prescribing information; December 2014.