Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 1;3:15032. doi: 10.1038/boneres.2015.32

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Sichuan University

This work is licensed under a Creative Commons Attribution 4.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Inhibition of collagen degradation affects the resorption pattern of BM and BC-derived OCs. BC-OCs (black squares) and BM-OCs (open circles) were generated from n different donors and cultured in the absence (–) or presence (+) of the specific CatK inhibitor L873724 (100 nmol·L⁻¹) on bone slices (3–8 slices per condition and preparation). The bone slices were analyzed for: (a) percentage of trenches per total eroded surface (BC: n = 10, BM: n = 8), (b) maximum demineralization depths of pits only (BC: n = 8, BM: n = 8), and (c) CTX release adjusted for eroded surface (BC: n = 6, BM: n = 4). Statistical analyses: Wilcoxon matched pairs test.