Table I.
CKD group without hemodialysis | Hemodialysis CKD group | |||||
---|---|---|---|---|---|---|
Variable | CKD3 | CKD4 | CKD5 | 1 | 2 | group |
Case number | 11 | 12 | 14 | 39 | 62 | 16 |
Gender (m/f) | 6/5 | 6/6 | 8/6 | 21/18 | 33/29 | 9/7 |
Age (years) | 39.8±4.9 | 48.0±4.9 | 38.8±17.5 | 47.5±23.8 | 53.5±21.9 | 37.6±10.5 |
BMI | 25.1±3.7 | 23.3±4.7 | 23.5±3.4 | 23.2±3.7 | 23.0±4.3 | 22.0±3.1 |
Dialysis time | ||||||
(months) | – | – | – | 40.1±15.9 | 39.8±15.7 | – |
Hb (g/l) | 128±22 | 107±14 | 92.7±19.4 | 87.5±17.6 | 104±7 | 123±20 |
HCT | 0.36±0.02 | 0.28±0.05 | 0.26±0.08 | 0.21±0.09 | 0.30±0.02 | 0.42±0.03 |
Alb (g/l) | 37.5±4.3a | 35.0±5.2a | 33.9±5.3a | 30.4±8.2a | 31.0±4.4a | 47.9±4.2 |
TC (mmol/l) | 4.59±1.02a | 4.88±1.10a | 5.04±1.19 | 5.28±1.37a | 5.37±1.36 | 4.27±1.41 |
TG (mmol/l) | 2.29±1.79a | 1.91±0.73a | 1.73±0.94a | 2.83±0.71a | 2.96±0.81a | 1.34±0.51 |
HDL (mmol/l) | 1.23±0.41a | 1.09±0.34a | 0.99±0.15a | 0.75±0.09a | 0.80±0.02a | 1.42±0.63 |
LDL (mmol/l) | 2.57±0.74a | 2.39±0.87a | 2.34±0.81a | 2.57±0.64a | 2.53±0.68a | 2.34±0.46 |
SCr (µmol/l) | 231±69a | 564±96a | 1280±311a | 793±296a | 776±258a | 60.8±10.6 |
CRP (mg/l) | 4.28±4.84a | 5.30±4.24a | 7.06±4.31a | 4.94±2.73ab | 5.23±3.19ab | 1.89±0.47 |
IL-6 (ng/ml) | 2.05±1.03a | 2.21±1.37a | 3.17±1.05a | 5.61±5.13ab | 5.42±5.53ab | 1.57±0.91 |
EPO (IU) | 1.58±0.22 | 1.76±0.68 | 1.83±1.12 | 1.91±1.37 | 1.97±1.23 | 1.45±1.02 |
Resistin (ng/ml) | 9.48±4.11a | 14.1±6.7a | 19.3±7.1a | 23.1±4.2ab | 22.6±5.6ab | 8.72±2.32 |
P<0.01 compared with the control group
P<0.01 compared with the group without dialysis. Data are presented as the mean ± standard deviation. CKD, chronic kidney disease; BMI, body mass index; Hb, hemaglobin; HCT, hematocrit; Alb, albumin; TC, total cholesterol; TG, triglycerides; HDL, high density lipoprotein; LDL, low density lipoprotein; SCr, serum creatinine; CRP, C-reactive protein; IL, interleukin; EPO, erythropoietin.