Table I.
Expression of mutant p53 and its association with the clinicopathological features of patients with oral squamous cell carcinoma.
| p53 expression | ||||
|---|---|---|---|---|
| Parameter | Cases, n | Negative | Positive | P-value |
| Age, years | >0.05 | |||
| ≥60 | 19 | 9 | 10 | |
| <60 | 32 | 18 | 14 | |
| Gender | >0.05 | |||
| Female | 14 | 8 | 6 | |
| Male | 37 | 19 | 18 | |
| Tumor differentiation | <0.05 | |||
| Well | 19 | 19 | 0 | |
| Moderate | 21 | 8 | 13 | |
| Poor | 11 | 0 | 11 | |
| Lymph node metastasis | <0.05 | |||
| No | 25 | 20 | 5 | |
| Yes | 26 | 7 | 19 | |
| Clinical stage | <0.05 | |||
| II | 18 | 15 | 3 | |
| III or IV | 33 | 12 | 21 | |
| Tumor site | >0.05 | |||
| Cheek | 15 | 7 | 8 | |
| Floor of mouth | 14 | 8 | 6 | |
| Tongue | 12 | 7 | 5 | |
| Palate | 5 | 3 | 2 | |
| Gum | 5 | 2 | 3 | |
| Therapeutic effectiveness | <0.05 | |||
| Responsive | 35 | 22 | 13 | |
| Non-responsive | 16 | 5 | 11 | |
χ2 test was performed for statistical analysis. P<0.05 was considered statistically significant.