Table II.
Serum creatinine and uNGAL values in cases and controls in the three samples.
| Time points | Cases (n=30) | Controls (n=20) | t-test value | P-value |
|---|---|---|---|---|
| First sample | ||||
| S. creatinine, mg/dl (range) | 0.41±0.1 (0.3–0.6) | 0.35±0.1 (0.2–0.5) | 1.24 | 0.168 |
| uNGAL, ng/ml (range) | 7.5±4.2 (4–22) | 3.6±1.2 (1.1–6.2) | 3.147 | <0.003 |
| Second sample | ||||
| S. creatinine, mg/dl (range) | 0.5±0.1 (0.3–0.8) | 0.36±0.13 (0.18–0.45) | 3.58 | <0.001 |
| uNGAL, ng/ml (range) | 31.3±17.3 (10–70) | 3.2±1.3 (1.4–5.2) | 5.122 | <0.001 |
| Third sample | ||||
| S. creatinine, mg/dl (range) | 0.6±0.12 (0.5–0.8) | 0.4±0.15 (0.2–0.7) | 5.4 | <0.001 |
| uNGAL, ng/ml (range) | 49.0±16.2 (16–82) | 3.5±1.6 (1.3–7) | 12.6 | <0.001 |
Data are mean ± standard deviation. First sample, baseline; second, one week after the initiation of chemotherapy; third; end of chemotherapy protocol. S. creatinine, serum creatinine; uNGAL, urinary neutrophil gelatinase-associated lipocalin.