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Effect of RAPA on osteosarcoma cell apoptosis. Osteosarcoma cells (MG63 and U-2 OS) were infected with miR-126-overexpressing or -silencing lentiviral vectors. The effect of RAPA on osteosarcoma cell apoptosis was then observed by flow cytometry. DDP, cisplatin; MTX, methotrexate; RAPA, rapamycin; pre-miR-126, osteosarcoma cells infected with miR-126-overexpressing lentiviral vectors; anti-miR-126, osteosarcoma cells infected with miR-126-silencing lentiviral vectors.
