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Effect of LW6 on the proliferation of activated T cells. (A) LW6 inhibits the proliferation of stimulated T cells. (B) Activation increased the level of c-Myc, a transcription factor required for cell proliferation, whereas treatment with LW6 decreased c-Myc levels. Assays were conducted in control (resting), activated and LW6-treated activated T cells. OD, optical density.
