TABLE 1.

Summary of sequencing reads from mRNA-seq sample sets

Parameter	Value for sample set
	1		2		3
	6 h	12 h	6 h	12 h	6	12
Ad6 infection
Total no. of reads	180,782,044	210,282,090	135,071,614	108,274,812	118,058,558	121,554,014
No. of reads used	180,463,643	209,914,762	134,893,355	108,130,934	117,900,862	121,404,039
Cellular results
Total no. of mapped reads	165,041,538	159,043,960	126,368,625	86,774,447	110,615,057	97,662,010
% of mapped reads	91.45	75.77	93.68	80.25	93.82	80.44
Viral results
Total no. of mapped reads	2,942,687	36,619,873	1,150,964	15,251,237	1,130,752	16,931,217
No. of properly paired mapped reads	2,755,224	34,702,806	1,070,978	14,227,066	1,051,572	15,817,326
% of mapped reads	1.63	17.45	0.85	14.10	0.96	13.95
Ad26 infection
Total no. of reads	196,950,760	198,932,178	135,228,756	116,166,350	110,402,754	131,713,602
No. of reads used	196,600,536	198,582,602	135,061,729	116,020,082	110,267,078	131,545,913
Cellular results
No. of mapped reads	182,415,868	160,373,156	127,298,181	105,704,250	103,757,608	120,185,933
% cellular mapped reads	92.79	80.76	94.25	91.11	94.10	91.36
Viral results
No. of mapped reads	2,226,651	25,852,093	179,986	3,955,512	143,315	4,005,895
No. of properly paired mapped reads	2,122,808	24,463,322	168,616	3,728,562	134,076	3,781,340
% of virus mapped	1.13	13.02	0.13	3.41	0.13	3.05
Mock infection
Total no. of reads	170,005,708	234,859,512	115,569,388	127,419,472	96,004,636	121,989,820
No. of reads used	169,674,316	234,389,298	115,423,082	127,271,387	95,892,810	121,848,550
Cellular results
No. of mapped reads	159,035,022	219,390,337	108,857,737	120,348,547	90,486,964	114,675,762
% cellular mapped reads	93.73	93.60	94.31	94.56	94.36	94.11
Viral results
No. of mapped reads	22	351	1,962	10	22	76
No. of properly paired mapped reads	22	322	686	10	22	72
% of virus mapped	0.00	0.00	0.00	0.00	0.00	0.00