Table II.
Frequency of the NBN variants and results of the logistic regression analysis performed in patients diagnosed with lung cancer versus healthy controls.
| Variant | Patients with lung cancer (%) | Healthy controls (%) | OR (95% CI) | P-value |
|---|---|---|---|---|
| p.I171V | 17/453 (3.75) | 12/2,400 (0.50) | 7.759 (3.679–16.360) | <0.0001a |
| c.657-661del | 3/453 (0.66) | 21/2,090 (1.00) | 0.657 (0.195–2.212) | 0.728 |
| p.R215W | 0/453 (0.00) | 1/498 (0.20) | 0.366 (0.015–9.006) | 1.000 |
NBN, nibrin; OR, odds ratio; CI, confidence interval.
a
Statistically significant difference.