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. 2015 Aug 28;10(5):2691–2698. doi: 10.3892/ol.2015.3654

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — miRNA-34a-5p may modulate the chemosensitivity of HCC cells through the JNK-Bcl-2 signaling pathway. Western blot analysis was performed to detect the expression of JNK, AKT, PI3K and Bcl-2, as well as the phosphorylation of JNK and AKT in HCC cells. NC, negative control; miRNA-34a-5p, microRNA-34a-5p; miR-34a, miRNA-34a; Si-NC, small interfering NC RNA; Si-AXL, small interfering RNA for AXL; JNK. c-Jun N-terminal kinase; p-JNK, phosphorylated JNK; Bcl-2; B-cell lymphoma 2; PI3K, phosphoinositide 3-kinase; p-AKT, phosphorylated AKT; HCC, hepatocellular carcinoma.