Table I.
Characteristics of the included studies.
| OS | DFS | |||||||
|---|---|---|---|---|---|---|---|---|
| First author, year | Population | Patients, n | Primer | Univariate analysis HR (95% CI) | Multivariate analysis HR (95% CI) | Univariate analysis HR (95% CI) | Multivariate analysis HR (95% CI) | (Refs.) |
| Sharma, 2014 | European | 39 | Esteller | 3.37 (0.23–50.02) | 6.2 (2–19.4) | N/A | 3.5 (1.3–9.8) | (20) |
| Ignatov, 2013 | European | 65 | Baldwin | N/A | N/A | 0.325 (0.16–0.662) | 0.224 (0.092–0.546) | (21) |
| Krasteva, 2012 | European | 135 | Baldwin | 0.47 (0.14–1.54) | 0.91 (0.24–3.41) | N/A | N/A | (22) |
| Xu, 2009 | European | 851 | Others | 1.72 (1.06–2.79) | 1.67 (0.99–2.81) | N/A | N/A | (23) |
| Xu, 2013 | Asian | 1,163 | Esteller | 1.29 (0.96–1.73) | N/A | 1.34 (1.06–1.71) | N/A | (24) |
| Hsu, 2013 | Asian | 139 | Esteller | N/A | 16.38 (1.37–195.45) | N/A | 12.19 (2.29–64.75) | (25) |
| Sharma, 2009 | Asian | 101 | Esteller | 5.06 (1.58–16.22) | 2.12 (0.47–9.63) | 3.88 (2.05–7.34) | 2.03 (0.96–4.29) | (26) |
| Chen, 2009 | Asian | 536 | Esteller | 1.56 (1.02–2.37) | 1.27 (0.81–1.99) | 1.45 (1.01–2.09) | 1.23 (0.84–1.8) | (27) |
| Jing, 2008 | Asian | 102 | Esteller | 6.4 (2.0–20.5) | N/A | N/A | N/A | (28) |
OS, overall survival; DFS, disease-free survival; HR, CI hazard ratio; CI, confidence interval.