Table I.
A, Distribution of prognostic factors | ||||
---|---|---|---|---|
Prognostic factors | Kagoshima | SSG | P-valuea | |
Skeletal metastasis | <0.01 | |||
Single | 65 | 146 | ||
Multiple | 80 | 505 | ||
Organ metastasis | <0.01 | |||
Absent | 107 | 384 | ||
Present | 38 | 267 | ||
Primary tumor | <0.01 | |||
Breast, kidney, thyroid, myeloma, lymphoma | 51 | 360 | ||
Other | 94 | 291 | ||
Karnofsky score | <0.01 | |||
≥70 | 26 | 338 | ||
<70 | 119 | 313 | ||
Impending fracture | 122 | 156 | <0.01 | |
Pathological fracture | 23 | 495 | ||
SSG survival score | ||||
Group A, 3–4 | 42 | N/A | ||
Group B, 1–2 | 90 | N/A | ||
Group C, 0 | 13 | N/A | ||
B, SSG survival scoring | ||||
Prognostic factors | Points | Sum | Groups | Estimated survival (months) |
Skeletal metastasis | >12 | |||
Single | 1 | |||
Multiple | 0 | 4 | A | |
Organ metastasis | 3–6 | |||
Absent | 1 | 3 | ||
Present | 0 | 2 | B | |
Breast, kidney, thyroid, myeloma, lymphoma | <3 | |||
Yes | 1 | 1 | ||
No | 0 | 0 | C | |
Karnofsky score | ||||
≥70 | 1 | |||
<70 | 0 | |||
C, SSG scoring | ||||
Prognostic score | Months | Survival rate (%) | 95% CI | |
Group A, 3–4 | 3 | 80.2 | 0.69–0.93 | |
6 | 65.5 | 0.50–0.81 | ||
12 | 59.0 | 0.43–0.75 | ||
24 | 27.4 | 0.10–0.44 | ||
Group B, 1–2 | 3 | 66.7 | 0.56–0.77 | |
6 | 55.5 | 0.44–0.67 | ||
12 | 32.6 | 0.21–0.44 | ||
24 | 26.0 | 0.15–0.37 | ||
Group C, 0 | 3 | 43.3 | 0.15–0.71 | |
6 | 8.7 | 0.00–0.25 |
Measured with Fisher's exact probability test. SSG, Scandinavian Sarcoma Group; CI, confidence interval.