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. 2015 Oct 8;10(6):2319–2324. doi: 10.3892/etm.2015.2789

Figure 4.

Figure 4.

Effect of BET domain family inhibition on the expression of TLR4/TRAF6/NF-κB in cardiomyocytes. Relative protein expression levels of (A) TLR4, (B) TRAF6 and (C) NF-κB in cardiomyocytes in the sham, AMI and AMI + JQ1 groups are shown. (D) Western blot, showing the protein expression in the sham (lane 1), AMI (lane 2) and AMI + JQ1 groups. *P<0.05 and #P<0.01 vs. sham group; @P<0.05 and &P<0.01 vs. AMI group. BET, bromodomain and extra-terminal; AMI, acute myocardial infarction; TLR4, Toll-like receptor 4; TRAF6, TNF receptor-associated factor 6; NF-κB, nuclear factor-κB; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.