Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic representation of murine prion protein (PrPC). Wild-type PrPC contains 4 tandem repeats approximating an octapeptide sequence, an hydrophobic core from amino acids 112 to 134 as well as 2 potential sites for glycosylation at N residues 180 and 196. Regions from 145 to 155, 175 to 193 and 200 to 219 from three alpha-helical structures, and helices II and III are disulfide bridged between C residues 178 and 213 [65]. Not to scale.
