Figure 3.

Radiation-induced depletion of bone marrow tissue with hematopoietic cells occurs in mice experienced hARS. Hematopoietic cells are indicated with white arrows in a “sham” specimen (left panel). Depletion with hematopoietic cells is observed after IR (ionizing irradiation ) with 9.5 Gy (gray). The myeloablation reveals the presence of the open reticular meshwork of the stromal cells. The stromal cells (in blue) are indicated with black arrows in the right panel. A large macrophage containing phagocytized hematopoietic cells is shown with a red arrow in the right panel. Collected at 22nd day following IR. Hematoxylin and eosin staining. Experimental conditions are indicated in Figure 1.