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Mitigation of total body irradiation damage to C3H/HeNHsd mice by intravenous JP4-039/F14 antioxidant small molecule therapy. Groups of C3H/HeNHsd mice (n = 15) received total body irradiation, and 24 h later intravenous administration of 100 μL of F14 liposomes containing 100 μg of JP4-039. Survival was quantitated, and there was a significant increase in survival in mice given JP4-039.
