Figure 12.

Infrared images of each microthermal cycler without heat sinks at the denaturing temperature. (a) 2-D temperature profile of the block-type microheaters. (b) 2-D temperature profile of the block-type microheaters with additional side heaters by applying an AC field. (c) 2-D temperature profile of the array-type microheaters with AC units. The dotted line shows the location of the PCR reaction chamber. The dimensions of each block in (a) are 2,900 µm × 6,000 µm, which are divided into grids (100 µm × 100 µm) with a spacing of 100 µm in (c). Reprinted from [12], Copyright 2008, with permission from Elsevier.