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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Physiol Behav. 2014 Apr 24;132:51–56. doi: 10.1016/j.physbeh.2014.04.029

Table 2.

Standardized regression coefficients (β) and R2 from hierarchical regression models for individual FTO SNPs predicting total energy intake, carbohydrate intake, fat intake, protein intake and sugar intake.a

rs9936768
52457064
rs8049933
52651631
rs7199716
52590749
rs12921970
52422727
rs12446047
52554803
rs11076022
52708479
Total Energy Intake (kcal)
RRVfoodb 0.371* 0.371* 0.371* 0.371* 0.371* 0.371*
SNP −0.111 0.024 0.129 0.096 −0.039 0.063
RRVfood x SNP −0.323** −0.295** 0.318** 0.294** 0.344** 0.306**
Total R2 0.206 0.191 0.216 0.205 0.211 0.203
Carbohydrate Intake (kcal)
RRVfood 0.367* 0.367* 0.367* 0.367* 0.367* 0.367*
SNP −0.109 0.018 0.127 0.098 −0.032 0.062
RRVfood x SNP −0.311** −0.284** 0.312** 0.295** 0.335** 0.297**
Total R2 0.201 0.186 0.213 0.205 0.206 0.199
Fat Intake (kcal)
RRVfood 0.375* 0.375* 0.375* 0.375* 0.375* 0.375*
SNP −0.114 0.029 0.132 0.094 −0.038 0.064
RRVfood x SNP −0.332** −0.305** 0.318** 0.293** 0.349** 0.311**
Total R2 0.208 0.193 0.216 0.204 0.212 0.203
Protein Intake (kcal)
RRVfood 0.289* 0.289* 0.289* 0.289* 0.289* 0.289*
SNP −0.117 0.012 0.133 0.122 −0.052 0.033
RRVfood x SNP −0.228 −0.231 0.294** 0.303** 0.287** 0.223
Total R2 0.172 0.164 0.203 0.206 0.183 0.165
Sugar Intake (kcal)
RRVfood 0.364* 0.364* 0.364* 0.364* 0.364* 0.364*
SNP −0.114 −0.012 0.133 0.105 −0.060 0.090
RRVfood x SNP −0.253 −0.246 0.216 0.276** 0.264** 0.270**
Total R2 0.199 0.189 0.202 0.214 0.199 0.207
*

p < 0.001

**

p < 0.000735 (corrected using false discovery estimates for the 68 FTO SNPs studied) using PLINK.

a

Controlled for proportion African, the highest reinforcement schedule of reading and BMI.

b

RRVfood = the highest reinforcement schedule completed for access to food or alternatives in the RRV task.